[e-ISSN : 2277-2782]

Anthelmintic Activity of Stem Bark Extract of Hugonia mystax Linn in Pheretima Posthuma - An In vitro Study

International Journal of Novel Trends in Pharmaceutical Sciences,2016,6,4,84-87.
Published:August 2016
Type:Research Article
Authors:
Author(s) affiliations:

N.Sundharajan1*, M.Mohankumar2, B.Vijayakumar3, S.Ruby4

*1Department of Pharmacoglogy, Nandha College of Pharmacy, Erode-638 052, Tamil Nadu, India.

2Raptim Research Limited, Navimumbai- 400707, Maharashtra,India.

3Department of Pharmaceutical Chemistry, Sri Venkateshwara College of Pharmacy, Chitoor, Andhra Pradesh, India.

4Department of Pharmaceutical Chemistry, Vinayaka Mission College of Pharmacy, Salem-638 052, Tamil Nadu, India

Abstract:

The aim of the present study was to evaluate the anthelmintic activity of stem bark extract of Hugonia mystax Linn in Pheretima posthuma. The preliminary phytochemical analysis of ethanolic extract of Hugonia mystax showed the presence of carbohydrates, flavonoids, steroids, saponins, terpenoids and absence of alkaloids, proteins and amino acids. The ethanolic extract acquired the Anthelmintic activity at the minimal dose of 25 mg/ml its significant activity (p<0.05) at 25 mg/ml for time taken to paralysis and death when compared to the standard drug Alendazole 10 mg/ml respectively. Based on the study, that ethanolic extract of stem bark of Hugonia mystax Linn has the maximum Anthelmintic activity potential and can be employed in human helminthes infections.

Anthelmintic activity of ethanolic extract of stem bark Hugonia mystax The anthelmintic