A Total of 140 cases on Drug Utilization Evaluation of Anti asthmatic drugs in the Tertiary care hospital have been presented by Observational study. Asthma has been growing in prevalence and has imposed an increasingly large burden on health services. The study was targeted to evaluate the drug utilization pattern in a tertiary care hospital and on educating the patient about the disease, medications in order to improve the health status and quality of life. The prospective evaluation anti asthmatic drug use in outpatient department of tertiary care hospital reveals that most utilized drug was oral preparations. The efficacy of various dosage regimens has been analyzed. The most commonly used drugs are methyl xanthenes, budenoside inhalers and combination of budenoside with a P agonist. Patient education and medication counseling are essential components in the management of disease like asthma.