[e-ISSN : 2277-2782]

Identification of Molecular Sequence Relationships between Culex quinquefasciatus and Aedes aegypti using Bioinformatics Techniques

International Journal of Novel Trends in Pharmaceutical Sciences,2015,64,3,64-69.
Published:June 2015
Type:Research Article
Authors:
Author(s) affiliations:

A. Joshua Andrews1*, Muthupandi M1, Ronald Nathanael S1, Junas Ekka1, Madavan S.P1 and John Williams. S2

1Research Scholar, School of Entomology and Centre for Natural Resources Management, P.G and Research Department of Advance Zoology and Biotechnology, Loyola College, Nungambakkam, Chennai- 600 034, Tamil Nadu, India.

2Associate Professor, School of Entomology and Centre for Natural Resources Management, P.G and Research Department of Advance Zoology and Biotechnology, Loyola College, Nungambakkam, Chennai- 600 034, Tamil Nadu, India.

Abstract:

When two symbolic representations of DNA or protein sequences are arranged next to one another so that their most similar elements are juxtaposed they are said to be aligned. Many bioinformatics tasks depend upon successful alignments. Alignments are conventionally shown as traces. In this research work we try to find out the molecular sequence similarity of Culex quinquefasciatus - multidrug resistance protein using bioinformatics techniques. The results obtained from our current researh explain how the Culex quinquefasciatus - multi drug resistance protein is molecularly related to Aedes aegypti species. We also represent the molecular functional part of the target protein sequences in culex and aedes species. In future, the same chemical compounds can be used to inhibit the protein targets of the two species using Cheminformatics studies.

Sequence Homology prediction (BLAST tool)