[e-ISSN : 2277-2782]

A Review on Diabetes Mellitus

International Journal of Novel Trends in Pharmaceutical Sciences,2015,5,6,201-217.
Published:June 2015
Type:Review Article
Author(s) affiliations:

K. Harikumar*, B. Kishore Kumar, G.J. Hemalatha, M. Bharath Kumar, Steven Fransis Saky Lado

Department of Pharmacology, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor, Andhra Pradesh-517127, INDIA.


Diabetes is a chronic disease that occurs when the pancreas does not generate enough insulin, or when the body cannot effectively use the insulin it produces. Hyperglycaemia, or raised blood sugar, is a common effect of uncontrolled diabetes and over time leads to severe damage to many of the body's systems, especially the nerves and blood vessels. DM can also occur secondary to genetic defects in beta cell function or insulin action, pancreatic diseases or other endocrinopathies, medications, toxic chemicals, or uncommon forms of immune-mediateddiabetes, e.g., "stiff man syndrome" or the presence of anti-insulinreceptor antibodies.

Pathophysiology Of Hyperglycaemia And Increased Circulating Fatty Acids in Type 2 Diabetes