[e-ISSN : 2277-2782]

Molecular Modelling and Insilico Drug Docking Studies on Breast Cancer Target Protein (TNRC9) using Cheminformatics Software and Tools

International Journal of Novel Trends in Pharmaceutical Sciences,2015,5,3,55-63.
Published:June 2015
Type:Research Article
Authors:
Author(s) affiliations:

Hemalatha. V 1, Sakila. L 2 and Balaji. M 3

1Post Graduate and Research Department of Zoology, Ethiraj College for Women, Chennai, Tamilnadu, India.

2Associate professor, Post Graduate and Research Department of Zoology, Ethiraj College for Women, Chennai, Tamilnadu, India.

3Senior Bioinformatician- Akshaya Computational Medicine Pvt, Ltd., Chennai, Tamilnadu, India.

Abstract:

In the world, breast cancer is the fifth most common cause of cancer death. In 2005, breast cancer caused 502,000 deaths (7% of cancer deaths; almost 1% of all deaths) in the world. Among all women in the world, breast cancer is the most common cancer. In this project we model the protein target for breast cancer and design the de novo drug which can be subjected to testing protocols by Clinical Pharmacology departments which would be of immense benefit in the treatment of cancer. Hence by way of our project we model the protein target and the designed drugs act as potential therapeutic agents for Clinical Oncological and Pharmacoinformatics studies.

Molecular Protein-Drug Docking (Discovery studio software)