[e-ISSN : 2277-2782]

Identification of Insilico Drugs and Drug Docking Studies on Hypothyroidism and Inferility Disorders in Human

International Journal of Novel Trends in Pharmaceutical Sciences,2015,5,3,42-54.
Published:June 2015
Type:Research Article
Authors:
Author(s) affiliations:

Anusha CS1,*, Halidha Z1, Radha T2 and Balaji M3

1Post Graduate and Research Department of Zoology, Ethiraj College for Women, Chennai, Tamilnadu, India.

2Associate Professor, Post Graduate and Research Department of Zoology, Ethiraj College for Women, Chennai, Tamilnadu, India.

3Senior Bioinformatician, Akshaya Computational Medicine Pvt, Ltd., Chennai, Tamilnadu, India.

Abstract:

Hypothyroidism is a common endocrine disorder in which the thyroid gland does not produce sufficient thyroid hormone. It can cause a number of symptoms, such as tiredness, poor ability to tolerate cold, and weight gain. In this insilico research, we identified protein target drugs have significant role in treating hypothyroidism and associated female and male infertility disorders. The designed de novo drugs show higher binding affinities when compared to the existing drugs. Hence by way of this project we discover de novo drugs which act as potential therapeutic agents in controlling Hypothyroidism.

3D Structure of Methyltestosterone drug