Histology is a usefultechnique for investigating the toxic effect of aquaticpollutants such a study also offers opportunity to locate the effect of pollutants in varies organs and systems of animals. Considerable interest has been show in recent years in histopathological studies while conducting toxicity test in fish. The present paper deals with the study on the effect of aquatic pollutant on histological variation of organs like liver and kidney in Anabas testudineus collected from the bukingham canal Chennai tamilnadu. The results revealed that the liver cells were degenerated with necrosis which appeared as focal areas with lymphocytic infiltration, marked cytoplasmic vacualation and fatty degeneration. The affected kidney tissue also exhibited degeneration and dissolution of epithelial cells of renal tubule vacualisation, loss of nuclei, shrunken and ruptured glomerulus at some places.