[e-ISSN : 2277-2782]

Lyophilization/Freeze Drying - An Review

International Journal of Novel Trends in Pharmaceutical Sciences,2013,3,4,87-98.
Published:October 2013
Type:Review Article
Author(s) affiliations:

GR. Nireesha1, L. Divya1, C.Sowmya2, N. Venkateshan3, M. Niranjan Babu4 and V. Lavakumar5*

1Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupathi, Andhra Pradesh, India.

2Faculty, Department of Pharmaceutics, OMER EL MUKHTAR University, Al-Beida, Libiya,  North Africa. 

3Department of Pharmaceutical Chemistry, Shankarlingam Bhuvaneswari College of Pharmacy, Sivakasi, Tamil Nadu,India.

4Principal, Seven Hills College of Pharmacy, Tirupathi, AP, India 5Research Director, Seven Hills College of Pharmacy, Tirupathi, Andhra Pradesh, India.


On 21st century, in pharmaceutical field lyophilization has become important subject to ongoing development and its expansion. Lyophilization is common, but cost intensive. In old days process optimization was focused only on drying rather than lyophilization. But lyophilization was more (or) equally important for the process of pharmaceuticals. This review focused on the recent advances and its targets in near future. At first, the principle, steps involved, formulation aspects and importance of lyophilization was explained.